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Model Challenge Targets

The eight targets chosen by the model challenge committee are shown below.  All are based on recently reported 3DEM structures.  The target order is according to unique molecular weight, from 19 kDa (TMV) at left to 2500 kDa (ribosome) at right. For challenge rules and additional information about each target see the model challenge guide.  

April 28: Corrected symmetry center info and BIOMT matrix files for the proteasome and beta-galactosidase targets, see the model challenge guide.

May 3: Corrected BIOMT matrix file containing Icosahedral transformations for Brome Mosaic Virus, see the model challenge guide.

Target Map Download: You can use this rsync script to download target maps from one of three wwPDB ftp sites. Alternately, you can download individual maps from EMDB atlas pages (click on EMDB entry link in the table below, select "download" tab).

  1. Tobacco Mosaic Virus 2. T20S Proteasome 3. GroEL 4. TRPV1 Channel 5. Brome Mosaic Virus 6. β-Galactosidase 7. γ-Secretase 8. 70S Ribosome

target

Map "A" EMDB entry
Primary Citation
Reported Resolution (Å)
EMD-2842
Fromm et al
3.3
EMD-5623
Li et al
3.3
EMD-6422
--
4.1
EMD-5778
Liao et al
3.3
EMD-6000
Wang et al
3.8
EMD-5995
Bartesaghi et al
3.2
EMD-2677
Lu et al
4.5
EMD-2847
Fischer et al
2.9
Map "B" EMDB entry
Primary Citation
Reported Resolution (Å)
  EMD-6287
Campbell et al
2.8
      EMD-2984
Bartesaghi et al
2.2

EMD-3061
Bai et al
3.4

EMD-6316
Li et al
3.6

Imposed Map Symmetry

Helical

Dihedral (D7)

Dihedral (D7)

 Cyclic (C4) Icosahedral (I)  Dihedral (D2) None (C1) None (C1)
 Sample MW (MDa) --  0.7 0.8  0.3  4.6  0.47  0.17 2.5
 Unique MW (kDa) 19  50 56  80 80  120  170 2500
Map Contributors (Thank You!)

Simon Fromm, Carsten Sachse

Jean-Paul Armache, Yifan Cheng

Melody Campbell, Bridget Carragher

Soung-Hun Roh, Corey Hryc, Wah Chiu Jean-Paul Armache, Maofu Liao, Yifan Cheng Zhao Wang, Wah Chiu Alberto Bartesaghi, Sriram Subramaniam Xiaochen Bai, Sjors Scheres

Niels Fischer, Holger Stark

Wen Li, Zheng Liu, Joachim Frank

EMDataBank Validation Challenges are supported by NIH National Institute of General Medical Sciences

Please send your challenge questions, comments and feedback to challenges@emdatabank.org

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