Model Challenge: Symmetry Info Updated

The model challenge guide now holds corrected symmetry center info and BIOMT matrices for the proteasome, GroEL, and β-galactosidase targets. The changes are highlighted with red text and update date.

The previously posted symmetry info had used rounded values for the voxel sizes, yielding inprecise center coordinate and matrix element values. We apologize for the errors.

Model Challenge Submission Deadline Extended

The deadline for model challenge submissions is now changed to Friday June 17 (21:00 UTC).

We hope that this extension will be helpful to all of our challengers.

In addition, please be aware that indicated symmetry centers in the model challenge guide may not be exact. 
This issue was just raised by one participant—we are investigating and will send a further update about this soon.

Further note (4/28): symmetry issue has been resolved

Map Submission Deadline Extended (Again)

By popular request, we are extending the map challenge submission deadline to April 15, 2016 @ 21:00 UTC (5 PM US ET).  Click here to see the new deadline time in your location.


Clarification about symmetry of the GroEL simulated data

The authors of the GroEL simulated dataset have asked us to let all map challenge participants know that 4HEL, the model from which the images were generated, is non-symmetrical, owing to unmatched crystallographic symmetry (P212121).   They have just become aware of this issue following discussion with two challenge participants.


Map Challenge

The Blind Assessment Phase is now open (Nov 2016-midFeb 2017).  Please visit the map challenge page for more details.

Model Challenge

The Challenge Phase for the 2015/2016 Model Challenge is now closed. Please visit the model challenge page for more details.


 Three-dimensional Electron Microscopy (3DEM) is becoming a key experimental method in Structural Biology. Recent advances in image acquisition and processing are yielding more structures determined at near-atomic resolution, as well as a wide range of macromolecular complexes and subcellular architectures determined at lower resolution.


A major goal of the EMDataBank team is to work with the 3DEM community to establish data validation methods that can be used in the structure determination process, define key indicators of a well-determined structure that should accompany every structure deposition, and implement appropriate validation procedures into a 3DEM validation pipeline. Following recommendations of the EM Validation Task Force (Henderson et al 2012), we are hosting new benchmark challenges here, with aim to stimulate further community discussions about validation procedures for 3DEM maps and map-derived models. Prior community-organized 3DEM challenge activities have included a Particle Picking Challenge (Zhu et al 2004),  CryoEM Modeling Challenge (Ludtke et al 2012), and CTF Challenge (Marabini et al 2015).

EMDataBank Validation Challenges are supported by NIH National Institute of General Medical Sciences

Please send your challenge questions, comments and feedback to

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